Feasibility and Safety of a Coaxial Dual Wavelength – Optical Coherence Tomography Apparatus – Doctor Thesis Luca Cedro, Dr. med.
Abstract - Congratulation to Dr Cedro for this great success! Purpose: To evaluate feasibility and safety of a coaxial dual wavelength optical coherence tomography (OCT) device (marked as Hydra-OCT). Methods: Healthy participants without ocular pathology underwent...
New Frontiers in Noninvasive Analysis of Retinal Wall-to-Lumen Ratio by Retinal Vessel Wall Analysis
Abstract Purpose: To compare measurement of wall-to-lumen ratio (WLR) by means of high-resolution adaptive optics imaging (AO) with intuitive to use retinal vessel wall (VW) analysis (VWA). Moreover, to validate the techniques by comparing WLR of healthy young (HY)...
Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas
Abstract Purpose: To compare spectral-domain (SD) and swept-source (SS) optical coherence tomography angiography (OCTA) for imaging retinal capillary hemangioblastomas (RCHs) in von Hippel-Lindau disease (VHLD). Methods: Prospective single-center cross-sectional...
Artificial intelligence in ophthalmology : Guidelines for physicians for the critical evaluation of studies
Abstract Background: Empirical models have been an integral part of everyday clinical practice in ophthalmology since the introduction of the Sanders-Retzlaff-Kraff (SRK) formula. Recent developments in the field of statistical learning (artificial intelligence, AI)...
Novel biomarker of sphericity and cylindricity indices in volume-rendering optical coherence tomography angiography in normal and diabetic eyes: a preliminary study
Abstract Purpose: Preliminary to evaluate geometric indices (vessel sphericity and cylindricity) for volume-rendered optical coherence tomography angiography (OCTA) in healthy and diabetic eyes. Methods: Twenty-six eyes of 13 healthy subjects and 12 eyes of patients...
Progression of Retinopathy Secondary to Maternally Inherited Diabetes and Deafness – Evaluation of Predicting Parameters
Abstract Purpose: To investigate the prognostic value of demographic, functional, and imaging parameters on retinal pigment epithelium (RPE) atrophy progression secondary to maternally inherited diabetes and deafness (MIDD) and to evaluate the application of these...
Macular Thickness Measurements of Healthy, naïve Cynomolgus Monkeys Assessed With Spectral-Domain Optical Coherence Tomography (SD-OCT)
Abstract The purpose of this study was to measure central macular thickness in an unprecedented number of cynomolgus monkeys. Macular thickness was measured with Heidelberg spectral-domain OCT in 320 eyes of healthy and treatment-naïve cynomolgus monkeys (80 males and...
New Technologies for Outcome Measures in Retinal Disease: Review From the European Vision Institute Special Interest Focus Group
Abstract Novel diagnostic tools to measure retinal function and structure are rapidly being developed and introduced into clinical use. Opportunities exist to use these informative and robust measures as endpoints for clinical trials to determine efficacy and to...
Publication: Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography
Authors: Petr Soukup; Peter Maloca; Bernd Altmann; Matthias Festag; Elke-Astrid Atzpodien; Simon Pot Abstract Purpose: The purpose of this study is to assess with spectral-domain optical coherence tomography (OCT) the interspecies variation of outer retinal...
Publication: Validation of automated artificial intelligence segmentation of optical coherence tomography images
Authors: Peter M. Maloca, Aaron Y. Lee, Emanuel R. de Carvalho, Mali Okada, Katrin Fasler, Irene Leung, Beat Hoermann, Pascal Kaiser, Susanne Suter, Pascal W. Hasler, Javier Zarranz-Ventura, Catherine Egan, Tjebo F. C. HeerenID,Konstantinos Balaskas, Adnan Tufail,...